Visualization of tumor heterogeneity by in situ padlock probe technology in colorectal cancer.

Tumor heterogeneity is considered a major cause for therapy resistance in colorectal cancer. Sub-populations of cells with different genetic alterations may exist in spatially distinct areas. Upon therapy, resistant sub-clones may enrich and ultimately lead to disease progression. Although ample dat...

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Bibliographic Details

Published in:	Histochemistry & Cell Biology Vol. 148; no. 2; pp. 105 - 116
Main Authors:	El-Heliebi, Amin, Kashofer, Karl, Fuchs, Julia, Jahn, Stephan, Viertler, Christian, Matak, Andrija, Sedlmayr, Peter, Hoefler, Gerald
Format:	Journal Article
Published:	Springer Nature Aug2017
Online Access:	View this record in EBSCOhost