Visualization of tumor heterogeneity by in situ padlock probe technology in colorectal cancer.
Tumor heterogeneity is considered a major cause for therapy resistance in colorectal cancer. Sub-populations of cells with different genetic alterations may exist in spatially distinct areas. Upon therapy, resistant sub-clones may enrich and ultimately lead to disease progression. Although ample dat...
| Publicado en: | Histochemistry & Cell Biology Vol. 148; no. 2; pp. 105 - 116 |
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| Autores principales: | , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Aug2017
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| Acceso en línea: | Ver este registro en EBSCOhost |