Effects of ewe's milk yogurt (whole and semi-skimmed) and cow's milk yogurt on inflammation markers and gut microbiota of subjects with borderline-high plasma cholesterol levels: a crossover study.
Purpose: Ewe's milk yogurt is richer in proteins, minerals and short- and medium-chain fatty acids compared to cow's milk yogurt. We aimed to evaluate the effects of cow's milk yogurt (CW, 3.0% fat), semi-skimmed (ES, 2.8% fat) and whole ewe's milk yogurts (EW, 5.8% fat) on inflammatory markers and...
| Publicado en: | European Journal of Nutrition Vol. 58; no. 3; pp. 1113 - 1125 |
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| Autores principales: | , , , , , , |
| Formato: | research tables/charts randomized controlled trial Journal Article |
| Publicado: |
Springer Nature
Apr2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=136223451&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 136223451 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 14366207 CR0 jtl: European Journal of Nutrition issn: 14366207 maglogo: N pubinfo: dt: Apr2019 vid: 58 iid: 3 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 136223451 136223451 136223451 10.1007/s00394-018-1626-0 136223451 ppf: 1113 ppct: 12 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Effects of ewe's milk yogurt (whole and semi-skimmed) and cow's milk yogurt on inflammation markers and gut microbiota of subjects with borderline-high plasma cholesterol levels: a crossover study. aug: au: Redondo, Noemí Diaz-Prieto, Ligia E. Olmedilla-Alonso, Begoña Nova, Esther García-González, Natalia Asensio-Vegas, Carmen Martín-Diana, Ana B. affil: Department of Metabolism and Nutrition, Institute of Food Science, Technology and Nutrition (ICTAN)-CSIC, C/ Jose Antonio Novais, 10, 28040, Madrid, Spain sug: subj: Sheep Yogurt Tissue Extracts Pharmacodynamics Inflammation Mediators Drug Effects Gut Microbiota Drug Effects Cholesterol Blood Human Randomized Controlled Trials Female Male Crossover Design Insulin Blood Leptin Blood Cell Adhesion Molecules Blood Cytokines Blood Polymerase Chain Reaction Methods Lipoproteins, HDL Cholesterol Blood Antigens, Surface Drug Effects Gram-Positive Bacteria Drug Effects Cytokines Drug Effects Female Male ab: Purpose: Ewe's milk yogurt is richer in proteins, minerals and short- and medium-chain fatty acids compared to cow's milk yogurt. We aimed to evaluate the effects of cow's milk yogurt (CW, 3.0% fat), semi-skimmed (ES, 2.8% fat) and whole ewe's milk yogurts (EW, 5.8% fat) on inflammatory markers and gut microbiota in subjects with borderline-high plasma cholesterol. Methodology: 30 adults (16 women) were randomized into a crossover study to consume 250 g/yogurt/day during three 5-week periods (4-week washouts). Plasma insulin, leptin, adhesion molecules, cytokines and gut microbiota composition (qPCR) were analysed. Rates of change were used to assess treatment effects both in the whole group and in subgroups of subjects with different cholesterol/HDL-c ratio (Cho-I group A: the top 6 women and 4 men values; Cho-I group B: remaining subjects). Results: The yogurts showed no different effects on the inflammatory biomarkers or the microbiota of the whole group. However, ICAM-1 and P-selectin rates of change were lower after EW compared to CW and ES, respectively, in subjects of the Cho-I group A (P = 0.047 and P = 0.020). Women of this group showed lower MCP-1 rates of change after EW compared to ES and CW (P = 0.028, both). Blautia coccoides–Eubacterium rectale decreased in women of the Cho-I group A during EW vs. ES (P = 0.028). Conclusion: Ewe's yogurt effects on inflammatory markers and microbiota were not different from those after cow's yogurt, but the attenuation of some inflammatory biomarkers with ewe's whole-milk yogurt in subjects with the highest TC/HDL-c deserves further study. pubtype: Academic Journal doctype: research tables/charts randomized controlled trial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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