Predicting mixed-meal measured glycaemic index in healthy subjects.
Purpose: To determine the influence of meal composition on the glycaemic impact of different carbohydrate staples, and the accuracy of "adjusted calculated meal GI" compared with "measured mixed-meal GI". Methods: In a non-blind randomized crossover trial fasted healthy subjects consumed four dinner...
| Publicado en: | European Journal of Nutrition Vol. 58; no. 7; pp. 2657 - 2668 |
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| Autores principales: | , , , , |
| Formato: | equations & formulas research tables/charts randomized controlled trial Journal Article |
| Publicado: |
Springer Nature
Oct2019
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=138885571&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 138885571 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 14366207 CR0 jtl: European Journal of Nutrition issn: 14366207 maglogo: N pubinfo: dt: Oct2019 vid: 58 iid: 7 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 138885571 138885571 144175122 138885571 10.1007/s00394-018-1813-z 138885571 ppf: 2657 ppct: 11 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Predicting mixed-meal measured glycaemic index in healthy subjects. aug: au: Ballance, Simon Knutsen, Svein Halvor Fosvold, Øivind Winther Fernandez, Aida Sainz Monro, John affil: Nofima AS, Norwegian Institute of Food, Fisheries and Aquaculture Research, Osloveien 1, 1433, Ås, Norway sug: subj: Glycemic Index Evaluation Blood Glucose Analysis Diet Food Human Randomized Controlled Trials Random Assignment Crossover Design Insulin Blood Restricted Diet Dietary Carbohydrates Administration and Dosage Meals Blood Analysis Glycemic Load Glucose Metabolism Postprandial Period Sweetened Beverages Treatment Outcomes ab: Purpose: To determine the influence of meal composition on the glycaemic impact of different carbohydrate staples, and the accuracy of "adjusted calculated meal GI" compared with "measured mixed-meal GI". Methods: In a non-blind randomized crossover trial fasted healthy subjects consumed four dinner-type mixed meals of realistic serving size comprising a carbohydrate staple of either mashed potato, pasta, rice or a glucose drink, combined with fixed portions of boiled carrots, poached salmon and herb sauce. Blood samples collected between 0 and 180 min were analysed for glucose and insulin concentrations. Adjusted calculated meal GI values were determined against a 50 g reference glucose drink, and compared to corresponding measured mixed-meal GIs, supplemented with data from four previous mixed-meal postprandial glycaemic response studies. Results: The common carbohydrate staples, and the glucose drink, ingested as part of the salmon mixed meal induced a significantly lower post-prandial relative glycaemic response (RGR) and concurrent higher relative insulin response than the same amount of staple eaten alone. Adjusted calculated mixed-meal GI closely predicted measured mixed-meal GI in healthy subjects for 15 out of 17 mixed meals examined, showing the need to account for effects of fat and protein when predicting measured mixed-meal GI. Further, we showed the validity of using customarily consumed food amounts in mixed-meal postprandial RGR study design. Conclusions: Adjusted calculated mixed-meal GI appears a useful model to predict measured mixed-meal GI in healthy subjects and with further development and validation could aid nutrition research and rational design of healthy meals for personalized nutrition and particular consumer groups. pubtype: Academic Journal doctype: equations & formulas research tables/charts randomized controlled trial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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