Insights in the Evaluation of Gluten Dietary Avoidance in Healthy Subjects.
Background: The amount of healthy subjects adopting a gluten-free diet (GFD) for nonmedical reasons actually surpasses the numbers of those who are dealing with a permanent gluten-related disorder.Objective: The study aimed to better clarify the interactions between a GFD and physical and psychologi...
| Published in: | Journal of the American College of Nutrition Vol. 39; no. 2; pp. 178 - 187 |
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| Main Authors: | , , , , , , , , , , , , |
| Format: | research tables/charts Journal Article |
| Published: |
Taylor & Francis Ltd
Feb2020
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=141718066&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 141718066 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 07315724 2QK8 jtl: Journal of the American College of Nutrition issn: 07315724 maglogo: Y pubinfo: dt: Feb2020 vid: 39 iid: 2 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 141718066 141718066 NLM31393225 141718066 10.1080/07315724.2019.1631902 NLM31393225 141718066 ppf: 178 ppct: 9 formats: tig: atl: Insights in the Evaluation of Gluten Dietary Avoidance in Healthy Subjects. aug: au: Campagna, Giovanna Tatangelo, Raffaella La Fratta, Irene Rizzuto, Alessia Ballerini, Patrizia Cocco, Domenico Savi, Samuele Rotunno, Antonio Rotunno, Pietro Falco Speranza, Lorenza Franceschelli, Sara Grilli, Alfredo Pesce, Mirko affil: School of Medicine and Health Science, University "G. d'Annunzio," Chieti, Italy sug: subj: Diet, Gluten-Free Statistics and Numerical Data Health Status Middle Age Patient Satisfaction Affect Female Body Image Diet, Gluten-Free Psychosocial Factors Diet Blood Cell Count Adult Italy Lipids Blood Celiac Disease Diet Therapy Male Research Subjects Human Energy Intake Blood Pressure Middle Aged: 45-64 years Adult: 19-44 years Female Male ab: Background: The amount of healthy subjects adopting a gluten-free diet (GFD) for nonmedical reasons actually surpasses the numbers of those who are dealing with a permanent gluten-related disorder.Objective: The study aimed to better clarify the interactions between a GFD and physical and psychological well-being.Methods: Sixty healthy subjects with normal weight were enrolled. Thirty subjects (15 female) were submitted to a normocaloric GFD and considered as the experimental group (EG), and 30 subjects (15 female) were submitted to a normocaloric diet (CG) for 6 months. The hematochemical and psychological parameters before and after the diet were recorded.Results: Significant improvement was demonstrated in red blood count, hemoglobin, total cholesterol, and high-density lipoprotein parameters in the EG after the gluten-free diet. However, a significant increase of α-amylase pancreatic activity and reduction of vitamin B12 and magnesium levels in the EG were observed. Regarding the psychological parameters, the GFD significantly improved scores assessing body satisfaction, but increased social insecurity.Conclusions: The study is the first to consider significant modulation in hematochemical parameters as well as psychological ones by gluten avoidance in healthy individuals. Although these subjects were not characterized by intestinal mucosa damage, some of the effects were similar to those observed in celiac disease patients who began to adhere to a GFD. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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