High Extra Virgin Olive Oil Consumption Is Linked to a Lower Prevalence of NAFLD with a Prominent Effect in Obese Subjects: Results from the MICOL Study.
Extra virgin olive oil (EVOO) has healthy benefits for noncommunicable diseases (NCDs). However, limited evidence is available about the effects of liver disease and non-alcoholic fatty liver disease (NAFLD). We evaluate whether dose-increased consumption of EVOO is associated with a lower prevalenc...
| Publicado en: | Nutrients Vol. 15; no. 21; pp. 4673 - 4684 |
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| Autores principales: | , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
MDPI
Nov2023
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=173567510&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 173567510 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 20726643 B0TT jtl: Nutrients issn: 20726643 maglogo: N pubinfo: dt: Nov2023 vid: 15 iid: 21 pid: 97109 pub: MDPI artinfo: ui: 173567510 173567510 173567510 10.3390/nu15214673 173567510 ppf: 4673 ppct: 11 formats: tig: atl: High Extra Virgin Olive Oil Consumption Is Linked to a Lower Prevalence of NAFLD with a Prominent Effect in Obese Subjects: Results from the MICOL Study. aug: au: Tedesco, Calogero Claudio. Bonfiglio, Caterina Notarnicola, Maria Rendina, Maria Castellaneta, Antonino Di Leo, Alfredo Giannelli, Gianluigi Fontana, Luigi affil: Data Science Unit, National Institute of Gastroenterology, IRCCS "Saverio de Bellis" Research Hospital, 70013 Castellana Grotte, Italy sug: subj: Nonalcoholic Fatty Liver Disease Epidemiology Nonalcoholic Fatty Liver Disease Prevention and Control Olive Oil Therapeutic Use Food Intake Obesity Olive Oil Administration and Dosage Dietary Fats Therapeutic Use Fatty Liver Physiopathology Fatty Liver Prevention and Control Funding Source Mediterranean Diet Odds Ratio Relative Risk Liver Diseases Diet Therapy Dose-Response Relationship Body Weight Classification Logistic Regression Confidence Intervals Human Male Female Adult Middle Age Aged Data Analysis Software Descriptive Statistics Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Male Female ab: Extra virgin olive oil (EVOO) has healthy benefits for noncommunicable diseases (NCDs). However, limited evidence is available about the effects of liver disease and non-alcoholic fatty liver disease (NAFLD). We evaluate whether dose-increased consumption of EVOO is associated with a lower prevalence of NAFLD and if these effects vary based on body weight. The study included 2436 subjects with a 33% NAFLD prevalence. Daily EVOO was categorized into tertiles: low (0–24 g/day), moderate (25–37 g/day), and high consumption (>37 g/day). Subjects were also classified by body mass index (BMI) as normo-weight (18.5–24.9), overweight (25–29.9), and obese (≥30). Logistic regression analysis was applied to calculate odds ratios (ORs) for NAFLD, considering a 20-gram increment in EVOO intake and accounting for EVOO categories combined with BMI classes. The ORs were 0.83 (0.74;0.93) C.I. p = 0.0018 for continuous EVOO, 0.89 (0.69;1.15) C.I. p = 0.37, and 0.73 (0.55;0.97) C.I. p = 0.03 for moderate and high consumption, respectively, when compared to low consumption. Overall, the percent relative risk reductions (RRR) for NAFLD from low to high EVOO consumption were 18% (16.4%;19.2%) C.I. and 26% (25%;27.4%) C.I. in overweight and obese subjects. High EVOO consumption is associated with a reduced risk of NAFLD. This effect is amplified in overweight subjects and even more in obese subjects. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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