Adding a Leafy Vegetable Fraction to Diets Decreases the Risk of Red Meat Mortality in MASLD Subjects: Results from the MICOL Cohort.

Background: Dietary guidelines recommend limiting red meat intake because it has been amply associated with increased cancer mortality, particularly in patients with liver conditions, such as metabolic dysfunction-associated fatty liver disease (MASLD). MASLD is the leading cause of liver dysfunctio...

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Publicado en:Nutrients Vol. 16; no. 8; pp. 1207 - 1219
Autores principales: Donghia, Rossella, Tatoli, Rossella, Campanella, Angelo, Cuccaro, Francesco, Bonfiglio, Caterina, Giannelli, Gianluigi
Formato: research tables/charts Journal Article
Publicado: MDPI Apr2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2024
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      pub: MDPI
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        atl: Adding a Leafy Vegetable Fraction to Diets Decreases the Risk of Red Meat Mortality in MASLD Subjects: Results from the MICOL Cohort.
      aug:
        au:
          Donghia, Rossella
          Tatoli, Rossella
          Campanella, Angelo
          Cuccaro, Francesco
          Bonfiglio, Caterina
          Giannelli, Gianluigi
        affil: National Institute of Gastroenterology—IRCCS "Saverio de Bellis", 70013 Castellana Grotte, Italy
      sug:
        subj:
          Food Intake
          Meat Adverse Effects
          Metabolic Diseases Risk Factors
          Nonalcoholic Fatty Liver Disease Risk Factors
          Nonalcoholic Fatty Liver Disease Mortality
          Nonalcoholic Fatty Liver Disease Diet Therapy
          Plant-Based Diet
          Mortality Prevention and Control
          Vegetables
          Plant Leaves
          Human
          Male
          Female
          Prospective Studies
          Descriptive Statistics
          Comparative Studies
          Life Style Changes
          Funding Source
          Neoplasms Mortality
          Male
          Female
      ab: Background: Dietary guidelines recommend limiting red meat intake because it has been amply associated with increased cancer mortality, particularly in patients with liver conditions, such as metabolic dysfunction-associated fatty liver disease (MASLD). MASLD is the leading cause of liver dysfunction in the world today, and no specific treatment other than lifestyle correction has yet been established. The aim of this study was to explore the protective role of leafy vegetables when associated with high red meat consumption. Methods: The study cohort included 1646 participants assessed during the fourth recall of the MICOL study, subdivided into two groups based on red meat intake (≤50 g/die vs. >50 g/die), in order to conduct a cancer mortality analysis. The prevalence of subjects that consumed >50 g/die was only 15.73%. Leafy vegetable intake was categorized based on median g/die consumption, and it was combined with red meat intake. Conclusions: This is the first study to demonstrate that the consumption of about 30 g/die of leafy vegetables reduces the risk of mortality. A strong association with mortality was observed in subjects with MASLD, and the protective role of vegetables was demonstrated.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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