Ultra-processed foods consumption and risk of age-related eye diseases: a prospective cohort study with UK biobank.

Purpose: Consumption of ultra-processed foods (UPF) has been associated with increased risks of various age-related diseases. However, the potential association between UPF consumption and age-related eye diseases (AREDs) remains unclear. We aim to assess the associations between consumption of UPF...

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Publicado en:European Journal of Nutrition Vol. 63; no. 8; pp. 3175 - 3187
Autores principales: Hu, Jianping, Yao, Yiran, Ge, Tongxin, Wang, Shaoyun, Liu, Shuyu, Zhu, Qiuyi, Song, Xin, Jia, Renbing, Zhuang, Ai
Formato: research tables/charts Journal Article
Publicado: Springer Nature Dec2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2024
      vid: 63
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s00394-024-03498-5
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        atl: Ultra-processed foods consumption and risk of age-related eye diseases: a prospective cohort study with UK biobank.
      aug:
        au:
          Hu, Jianping
          Yao, Yiran
          Ge, Tongxin
          Wang, Shaoyun
          Liu, Shuyu
          Zhu, Qiuyi
          Song, Xin
          Jia, Renbing
          Zhuang, Ai
        affil: Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, 200011, Shanghai, PR China
      sug:
        subj:
          Food, Commercially Packaged Adverse Effects
          Food Intake
          Eye Diseases Risk Factors
          Risk Assessment
          Human
          Funding Source
          United Kingdom
          Male
          Female
          Middle Age
          Aged
          Macular Degeneration Risk Factors
          Cataract Risk Factors
          Glaucoma Risk Factors
          Cox Proportional Hazards Model
          Descriptive Statistics
          Confidence Intervals
          Aging
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: Purpose: Consumption of ultra-processed foods (UPF) has been associated with increased risks of various age-related diseases. However, the potential association between UPF consumption and age-related eye diseases (AREDs) remains unclear. We aim to assess the associations between consumption of UPF and risk of AREDs including age-related macular degeneration (AMD), cataract and glaucoma. Methods: We included 156,232 individuals aged 50 or older, who were free from AREDs from UK biobank study. Dietary intake data were collected using 24-h dietary assessments. UPF is defined according to the NOVA classification, and all participants are divided into four quartiles based on the weight proportion (%) of UPF. During a median of 10 years of follow-up. Cox proportional hazards were used to estimate the association between the proportion of UPF in the diet and the subsequent risk of various AREDs. Results: After adjusting for multiple variables, individuals in the highest quartiles for UPF consumption exhibited an increased risk of AMD (hazard ratio (HR): 1.28; 95% confidence interval (CI): 1.01–1.63; p = 0.03), cataract (HR: 1.10; 95% CI: 1.01–1.20; p = 0.04), and glaucoma (HR: 1.27; 95% CI: 0.98–1.63; p = 0.06) compared to those in the lowest quartiles. Moreover, a 10% increase in the weight of UPF in diet was associated with an 8% higher risk of AMD (HR: 1.08; 95% CI: 1.01–1.15; p = 0.03), a 3% higher risk of cataract (HR: 1.03; 95% CI: 1.00–1.06; p = 0.04), and a 7% higher risk of glaucoma (HR: 1.07; 95% CI: 1.00–1.15; p = 0.05). Conclusion: Our results suggest that a higher proportion of UPF in the diet was significantly link with an elevated risk of AMD and cataract. While additional research is necessary to validate these findings in diverse populations and settings, these results offer initial evidence to endorse public health initiatives that encourage limiting consumption of UPF.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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