Ecthyma gangrenosum in a neutropenic patient.

The article focuses on a case of ecthyma gangrenosum in a 60-year-old woman with acute myeloid leukemia undergoing induction chemotherapy and moderate neutropenia. The patient developed a painful, necrotic skin lesion on the left tibia, which improved rapidly after empirical treatment with piperacil...

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Detalles Bibliográficos
Publicado en:Infection Vol. 54; no. 4; pp. 2153 - 2154
Autores principales: Misin, Andrea, Di Bella, Stefano
Formato: case study pictorial Journal Article
Publicado: Springer Nature Aug2026
Acceso en línea:Ver este registro en EBSCOhost
Descripción
Sumario:The article focuses on a case of ecthyma gangrenosum in a 60-year-old woman with acute myeloid leukemia undergoing induction chemotherapy and moderate neutropenia. The patient developed a painful, necrotic skin lesion on the left tibia, which improved rapidly after empirical treatment with piperacillin/tazobactam. Blood cultures and fungal biomarkers were negative, but bacterial culture of a skin biopsy confirmed Pseudomonas aeruginosa infection. The report emphasizes that in immunocompromised patients, rapidly progressing necrotic skin lesions should prompt immediate diagnostic evaluation and empirical antipseudomonal therapy.