Ecthyma gangrenosum in a neutropenic patient.

The article focuses on a case of ecthyma gangrenosum in a 60-year-old woman with acute myeloid leukemia undergoing induction chemotherapy and moderate neutropenia. The patient developed a painful, necrotic skin lesion on the left tibia, which improved rapidly after empirical treatment with piperacil...

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Publicado en:Infection Vol. 54; no. 4; pp. 2153 - 2154
Autores principales: Misin, Andrea, Di Bella, Stefano
Formato: case study pictorial Journal Article
Publicado: Springer Nature Aug2026
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
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        atl: Ecthyma gangrenosum in a neutropenic patient.
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        au:
          Misin, Andrea
          Di Bella, Stefano
        affil: https://ror.org/05g7qp006 Infectious Diseases Unit, Trieste University Hospital (ASUGI), Trieste, Italy
      sug:
        subj:
          Pyoderma Gangrenosum Diagnosis
          Neutropenia
          Leukemia, Myeloid, Acute
          Female
          Middle Age
          Tibia
          C-Reactive Protein Blood
          Pseudomonas Infections
          Pyoderma Gangrenosum Drug Therapy
          Antiinfective Agents Therapeutic Use
          Ampicillin
          Immunocompromised Host
          Middle Aged: 45-64 years
          Female
      ab: The article focuses on a case of ecthyma gangrenosum in a 60-year-old woman with acute myeloid leukemia undergoing induction chemotherapy and moderate neutropenia. The patient developed a painful, necrotic skin lesion on the left tibia, which improved rapidly after empirical treatment with piperacillin/tazobactam. Blood cultures and fungal biomarkers were negative, but bacterial culture of a skin biopsy confirmed Pseudomonas aeruginosa infection. The report emphasizes that in immunocompromised patients, rapidly progressing necrotic skin lesions should prompt immediate diagnostic evaluation and empirical antipseudomonal therapy.
      pubtype: Academic Journal
      doctype:
        case study
        pictorial
        Journal Article
      ougenre: Article
    language: English
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