Ecthyma gangrenosum in a neutropenic patient.
The article focuses on a case of ecthyma gangrenosum in a 60-year-old woman with acute myeloid leukemia undergoing induction chemotherapy and moderate neutropenia. The patient developed a painful, necrotic skin lesion on the left tibia, which improved rapidly after empirical treatment with piperacil...
| Published in: | Infection Vol. 54; no. 4; pp. 2153 - 2154 |
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| Main Authors: | , |
| Format: | case study pictorial Journal Article |
| Published: |
Springer Nature
Aug2026
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| Online Access: | View this record in EBSCOhost |
| Summary: | The article focuses on a case of ecthyma gangrenosum in a 60-year-old woman with acute myeloid leukemia undergoing induction chemotherapy and moderate neutropenia. The patient developed a painful, necrotic skin lesion on the left tibia, which improved rapidly after empirical treatment with piperacillin/tazobactam. Blood cultures and fungal biomarkers were negative, but bacterial culture of a skin biopsy confirmed Pseudomonas aeruginosa infection. The report emphasizes that in immunocompromised patients, rapidly progressing necrotic skin lesions should prompt immediate diagnostic evaluation and empirical antipseudomonal therapy. |
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