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Imaging Cell Surface Glycans with Bioorthogonal Chemical Reporters.

The article discusses a study that introduces two different chemical reporters into sialic acid and N-acetylgalactosamine residues and then simultaneously imaged their associated cell surface glycans with fluorescent probes. In this study, the two chemical reporters used are the ketone and the azide...

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Published in:Journal of the American Chemical Society Vol. 129; no. 27; pp. 8400 - 8402
Main Authors: Chang, Pamela V., Prescher, Jennifer A., Hangauer, Matthew J., Bertozzi, Carolyn R.
Format: Article
Published: American Chemical Society 7/11/2007
Subjects:
Polysaccharides
Azides
Ketones
Cell membranes
Fluorescent probes
Imaging systems
Sialic acids
Online Access:View this record in EBSCOhost

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