The Catalytic Mechanism of an Aspartic Proteinase Explored with Neutron and X-ray Diffraction.

The article discusses a study on the catalytic mechanism of an aspartic proteinase, explored with neutron and x-ray diffraction. Aspartic proteinases have a proven therapeutic effect in the treatment of AIDS. Mechanistic proposals were made based on X-ray diffraction studies. The results suggest tha...

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Publicado en:	Journal of the American Chemical Society Vol. 130; no. 23; pp. 7235 - 7238
Autores principales:	Coates, Leighton, Han-Fang Tuan, Tomanicek, Stephen, Kovalevsky, Andrey, Mustyakimov, Marat, Erskine, Peter, Cooper, Jon
Formato:	Artículo
Publicado:	American Chemical Society 6/11/2008
Materias:	Aspartic proteinases Optical diffraction Neutrons Catalysts AIDS
Acceso en línea:	Ver este registro en EBSCOhost