Detection of Single-Molecule DNA Hybridization Using Enzymatic Amplification in an Array of Femtoliter-Sized Reaction Vessels.
The article features a highly sensitive single-molecule readout system which detects deoxyribonucleic acid (DNA) hybridization using enzymatic signal amplification in an array of entoleter-sized reaction vessels. A fiber optic array was employed to validate the utility of the technology. An overview...
| Publicado en: | Journal of the American Chemical Society Vol. 130; no. 38; pp. 12622 - 12624 |
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| Autores principales: | , , |
| Formato: | Artículo |
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American Chemical Society
9/24/2008
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=hlh&AN=34491653&site=ehost-live header: @attributes: shortDbName: hlh uiTerm: 34491653 longDbName: Humanities International Complete uiTag: AN controlInfo: bkinfo: jinfo: jid: 00027863 ACS jtl: Journal of the American Chemical Society issn: 00027863 maglogo: N pubinfo: dt: 9/24/2008 vid: 130 iid: 38 pid: 997 pub: American Chemical Society artinfo: ui: 34491653 10.1021/ja8053018 ppf: 12622 ppct: 2 formats: tig: atl: Detection of Single-Molecule DNA Hybridization Using Enzymatic Amplification in an Array of Femtoliter-Sized Reaction Vessels. aug: au: Zhaohui Li Hayman, Ryan B. Walt, David R. affil: Department of Chemistry, Tufts University, 62 Talbot Avenue, Medford, Massachusetts 02155, USA su: DNA Molecular biology Nucleic acid hybridization Fiber optics Array processors Molecular genetics sug: subj: DNA Molecular biology Nucleic acid hybridization Fiber optics Array processors Molecular genetics ab: The article features a highly sensitive single-molecule readout system which detects deoxyribonucleic acid (DNA) hybridization using enzymatic signal amplification in an array of entoleter-sized reaction vessels. A fiber optic array was employed to validate the utility of the technology. An overview of the procedures of the experiment undertaken is also provided. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: Y dt: @attributes: year: 2008 holdings: @attributes: islocal: N |
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