Fluorescent Ratiometric MFC Probe Sensitive to Early Stages of α-Synuclein Aggregation.

The article focuses on the sensor molecules consisting of covalent adducts of Ala-to-Cys mutants of the 140aa protein a-synuclein (AS) with thiol-reactive (maleimide) probe (MFC) based on 2-(2-furyl)-3-hydroxychromones (FC). It says that AS140-MFC is sensitive to the early and intermediate stages of...

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Publicado en:	Journal of the American Chemical Society Vol. 132; no. 23; pp. 7860 - 7862
Autores principales:	Yushchenko, Dmytro A., Fauerbach, Jonathan A., Thirunavukkuarasu, hyamala, Jares-Erijman, Elizabeth A., Jovin, Thomas M.
Formato:	Artículo
Publicado:	American Chemical Society 6/16/2010
Materias:	Thiols Clustering of particles Intermediates (Chemistry) Molecules Fire assay Sampling (Process) Protein synthesis
Acceso en línea:	Ver este registro en EBSCOhost