Discrete Bimodal Probes for Thrombus Imaging.

Here we report a generalizable solid/solution-phase strategy for the synthesis of discrete bimodal fibrin-targeted imaging probes. A fibrin-specific peptide was conjugated with two distinct imaging reporters at the C- and N-termini. In vitro studies demonstrated retention of fibrin affinity and spec...

Descripción completa

Detalles Bibliográficos

Publicado en:	Journal of the American Chemical Society Vol. 134; no. 26; pp. 10799 - 10803
Autores principales:	Uppal, Ritika, Ciesienski, Kate L., Chonde, Daniel B., Loving, Galen S., Caravan, Peter
Formato:	Artículo
Publicado:	American Chemical Society 7/4/2012
Materias:	Diagnostic equipment Molecular probes Fibrin Thrombosis diagnosis Imaging systems Positron emission tomography Magnetic resonance imaging Optical images
Acceso en línea:	Ver este registro en EBSCOhost