Indolactam-V Is Involved in the CH/x Interaction with Pro-I I of the PKCδ C1B Domain: Application for the Structural Optimization of the PKCδ Ligand.
The article presents information on protein kinase C (PKC) isozymes are the main receptors of tumor promoters such as phorbol esters and teleocidins. After hydrolysis of the acetal, the asymmetric Strecker reaction was applied to the resulting aldehyde to give an (R)-amino nitrile diastereoselectiv...
| Publicado en: | Journal of the American Chemical Society Vol. 127; no. 16; pp. 5746 - 5748 |
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| Autores principales: | , , , , |
| Formato: | Artículo |
| Publicado: |
American Chemical Society
4/27/2005
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| Materias: | |
| Acceso en línea: | Ver este registro en EBSCOhost |